4 Challenges and future directions 4.1 Safety considerations The safety profile of dual or triple receptor agonists targeting GLP-1, GIP, and GCG receptors in the treatment of MASLD and related metabolic disorders warrants careful evaluation
PubMed Sedel F, Papeix C, Bellanger A, Touitou V, Lebrun-Frenay C, Galanaud D, et al
For example, extended, repeated, or poorly managed antibiotic use in dogs can contribute to antimicrobial resistance (AMR), especially for chronic conditions requiring extended therapy, such as recurrent skin infections, urinary tract infections, or osteomyelitis (21)
A dual GIP and GLP-1 receptor agonist developed by Eli Lilly, Tirzepatide, has demonstrated weight loss results up to 22.5% in diabetes and obesity management